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It examines tyrosinase inhibitors, which are still widely used to manage hyperpigmentation problems, as well as new compounds targeting downstream pathways

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doi: 10.3389/fphys.2025.1584195 Received 27 February 2025 Accepted 21 May 2025 Published 01 July 2025 Volume 16 - 2025 Edited by Walter Swardfager, University of Toronto, Canada Reviewed by Andrea Deledda, Azienda Ospedaliero-Universitaria Cagliari, Italy Natasha Anita, University of California, San Diego, United States Updates Copyright 2025 Hinman, Alan and Lee

S2CID 21994642

Acknowledgements Thanks to Dr

(38683591) However, in highly complex patients who are at risk of over-sedation, PRN short-acting opioids may be safer